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Hypertension in children. Increased efficacy of technetium Tc/sup 99m/ succimer in screening for renal disease

Journal Article · · Am. J. Dis. Child.; (United States)
; ;
Renal scintigraphy with technetium Tc-99m succimer (DMSA) and technetium Tc-99m pentetate (DTPA) was used to study 80 hypertensive pediatric and adolescent patients. Renal abnormalities such as asymmetry of function, size, or shape were identified in 13 patients. Both excretory urography and technetium Tc-99m pentetate studies were successful in detecting 54% of the abnormalities in patients studied; technetium Tc-99m succimer identified 92%. The accuracy of the latter was 96%, with a specificity of 97%. The ability of technetium Tc-99m succimer renal scintigraphy to identify accurately the presence or absence of renal abnormalities warrants its inclusion in the initial examination of pediatric and adolescent patients with hypertension.
Research Organization:
Children's Hospital, Boston, MA
OSTI ID:
5779054
Journal Information:
Am. J. Dis. Child.; (United States), Journal Name: Am. J. Dis. Child.; (United States) Vol. 139:2; ISSN AJDCA
Country of Publication:
United States
Language:
English

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Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
AMINO ACIDS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACIDS
CARDIOVASCULAR DISEASES
CHELATING AGENTS
CHILDREN
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DICARBOXYLIC ACIDS
DISEASES
DOCUMENT TYPES
DRUGS
DTPA
HOURS LIVING RADIOISOTOPES
HYPERTENSION
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
PATENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOPROTECTIVE SUBSTANCES
SCINTISCANNING
SUCCINIC ACID
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
THIOLS
UROGENITAL SYSTEM DISEASES
VASCULAR DISEASES
YEARS LIVING RADIOISOTOPES