Prediction of language and neurologic recovery after cerebral infarction with SPECT imaging using N-isopropyl-p-(I-123) iodoamphetamine
Journal Article
·
· Arch. Neurol.; (United States)
Fourteen patients (10 with left-sided and 4 with right-sided cerebral infarction) were prospectively studied with single-photon emission computed tomography (SPECT) using N-isopropyl-p-(I-123) iodoamphetamine (IMP, SPECTamine) to determine its usefulness in predicting neurologic/language recovery after cerebral infarction. All neuro-SPECT imaging was performed within 30 days after infarction. Detailed assessment of neurologic and/or language recovery (after 3 months) was carried out prospectively in each patient. Patients with smaller volume IMP defects in the region of infarction demonstrated significantly better neurologic and language recovery than patients with large IMP defects. Analysis of the IMP ''redistribution'' phenomenon failed to demonstrate definitively a relationship with clinical recovery. It was concluded that the volume of the IMP defect can aid in predicting recovery potential after cerebral infarction.
- Research Organization:
- Hines Veterans Administration Hospital, IL (USA)
- OSTI ID:
- 5766954
- Journal Information:
- Arch. Neurol.; (United States), Journal Name: Arch. Neurol.; (United States) Vol. 46:6; ISSN ARNEA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Assessment of regional cerebral blood flow (rCBF) in stroke using SPECT and N-isopropyl-(I-123)-p-iodoamphetamine (IMP)
Critical cerebral blood flow thresholds studied by SPECT using xenon-133 and iodine-123 iodoamphetamine
Caudate nucleus infarction demonstrated by N-isopropyl-p iodoamphetamine SPECT imaging using a rotating gamma camera
Journal Article
·
· Stroke; (United States)
·
OSTI ID:6749503
Critical cerebral blood flow thresholds studied by SPECT using xenon-133 and iodine-123 iodoamphetamine
Journal Article
·
Tue Feb 28 23:00:00 EST 1989
· J. Nucl. Med.; (United States)
·
OSTI ID:5601967
Caudate nucleus infarction demonstrated by N-isopropyl-p iodoamphetamine SPECT imaging using a rotating gamma camera
Journal Article
·
Wed Oct 01 00:00:00 EDT 1986
· Clin. Nucl. Med.; (United States)
·
OSTI ID:6850105
Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AMPHETAMINES
ANALEPTICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM AGENTS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
FORECASTING
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
RECOVERY
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
SYMPATHOMIMETICS
TOMOGRAPHY
62 RADIOLOGY AND NUCLEAR MEDICINE
AMPHETAMINES
ANALEPTICS
AUTONOMIC NERVOUS SYSTEM AGENTS
BETA DECAY RADIOISOTOPES
BIOLOGICAL RECOVERY
BODY
BRAIN
CENTRAL NERVOUS SYSTEM
CENTRAL NERVOUS SYSTEM AGENTS
COMPUTERIZED TOMOGRAPHY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
FORECASTING
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
IODINE 123
IODINE ISOTOPES
ISOTOPES
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPES
RECOVERY
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
SYMPATHOMIMETICS
TOMOGRAPHY