Radionuclide angiography in evaluation of left ventricular function following aortic valve replacement

Journal Article · Fri May 01 04:00:00 EDT 1981 · Ann. Thorac. Surg.; (United States)

DOI:https://doi.org/10.1016/S0003-4975(10)60990-3· OSTI ID:5764396

Santinga, J T; Kirsh, M M; Brady, T J; Thrall, J; Pitt, B

Congestive heart failure in patients surviving aortic valve replacement has been associated with a high late mortality. To determine whether myocardial dysfunction in these patients occurred preoperatively, perioperatively, or during the early postoperative period, 19 consecutive patients undergoing aortic valve replacement using cardioplegia and hypothermia were studied by multiple-gated cardiac blood pool imaging. The resting ejection fractions for 8 patients with aortic stenosis did not show significant changes following operation. The 11 patients with aortic insufficiency has resting preoperative values of 58 +/- 15%, which fell to 38 +/- 18% immediately postoperatively (p less than 0.01), with the late values being 51 +/- 16%. Eight of 18 patients (44%) showed deterioration of regional wall motion immediately after operation, which persisted in 3 during the late evaluation. The occurrence of new perioperative regional wall motion abnormalities and persistent perioperative depression in left ventricular function in some patients suggest the need for further improvement in myocardial protection during cardiopulmonary bypass for aortic valve replacement.

• Research Organization: Univ. of Michigan, Ann Arbor
• OSTI ID: 5764396
• Journal Information: Ann. Thorac. Surg.; (United States), Journal Name: Ann. Thorac. Surg.; (United States) Vol. 31:5; ISSN ATHSA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
AORTA
ARTERIES
BLOOD VESSELS
BODY
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
HEART
HEART FAILURE
ISOTOPE APPLICATIONS
LABELLED POOL TECHNIQUES
MEDICINE
MUSCLES
MYOCARDIUM
ORGANS
PATHOLOGY
PATIENTS
RADIOISOTOPE SCANNING
SCINTISCANNING
SURGERY
SYMPTOMS
TRACER TECHNIQUES