Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Predicting the extent and location of coronary artery disease during the early postinfarction period by quantitative thallium-201 scintigraphy

Journal Article · · Am. J. Cardiol.; (United States)

The ability of quantitative thallium-201 scintigraphy to predict the extent and location of coronary artery disease before hospital discharge after acute myocardial infarction was evaluated in 52 patients. All patients underwent coronary angiography and serial thallium-201 imaging either at rest (10 patients) or after submaximal exercise stress (42 patients; target heart rate 120 beats/min). Two or three vessel disease was designated if abnormal thallium-201 uptake or washout patterns, or both, were seen in two or three vascular segments, respectively. Thus, 2 weeks after myocardial infarction, exercise thallium-201 scintigraphy is useful for predicting the extent and location of coronary artery disease, particularly stenoses in the left anterior descending and right coronary arteries. Moreover, thallium-201 imaging at rest is reliable in assessing the extent of coronary disease in hospitalized patients who cannot undergo exercise testing because of unstable angina, uncompensated heart failure, poorly controlled arrhythmias or physical limitations.

Research Organization:
Univ. of Virginia, Charlottesville
OSTI ID:
5764382
Journal Information:
Am. J. Cardiol.; (United States), Journal Name: Am. J. Cardiol.; (United States) Vol. 47:5; ISSN AJCDA
Country of Publication:
United States
Language:
English