Floor of mouth cancer: patient selection and treatment results

Journal Article · Fri Apr 01 04:00:00 EST 1983 · Laryngoscope; (United States)

OSTI ID:5763227

Marks, J E; Lee, F; Smith, P G; Ogura, J H

Retrospective review of 126 primarily treated floor of mouth (FOM) cancers was done to study patient selection and to search for more optimum treatment strategies. Small surface lesions were treated by local excision (LE); small lesions invading FOM without lymph nodes were treated by radiation alone (RA), while larger lesions and those with palpable nodes were treated by preoperative irradiation and surgery (R + S). Ultimate control of the FOM cancer and nodes was achieved for 100% of the LE, 71% of the RA, and 75% of the R + S patients. The majority of primary tumor and nodal recurrences developed by 15 months and 35% of the failures were salvaged by additional treatment. Change in treatment strategies are suggested for surface lesions because of a poor rate of initial tumor control (43%), for patients treated by RA because of a high rate of complications (41%), and for patients without palpable lymph nodes who can be successfully treated by elective neck irradiation.

• Research Organization: Mallinckrodt Institute of Radiology, St. Louis, MO
• OSTI ID: 5763227
• Journal Information: Laryngoscope; (United States), Journal Name: Laryngoscope; (United States) Vol. 93:4; ISSN LARYA
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
BODY AREAS
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
IRRADIATION
MEDICINE
NECK
NEOPLASMS
NUCLEAR MEDICINE
ORAL CAVITY
PATIENTS
RADIOLOGY
RADIOTHERAPY
SURGERY
THERAPY