Midi-maxi computer interaction in the interpretation of nuclear medicine procedures
A study of renal function with an Anger Gamma Camera coupled with a Digital Equipment Corporation Gamma-11 System and an IBM System 370 demonstrates the potential of quantitative determinations of physiological function through the application of midi-maxi computer interaction in the interpretation of nuclear medicine procedures. It is shown that radiotracers can provide an opportunity to assess physiological processes of renal function by noninvasively following the path of a tracer as a function of time. Time-activity relationships obtained over seven anatomically defined regions are related to parameters of a seven compartment model employed to describe the renal clearance process. The values obtained for clinically significant parameters agree with known renal pathophysiology. Differentiation of failure of acute, chronic, and obstructive forms is indicated.
- Research Organization:
- Missouri Univ., Columbia (USA)
- OSTI ID:
- 5761012
- Resource Relation:
- Other Information: Thesis (Ph. D.)
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
59 BASIC BIOLOGICAL SCIENCES
99 GENERAL AND MISCELLANEOUS//MATHEMATICS, COMPUTING, AND INFORMATION SCIENCE
NUCLEAR MEDICINE
COMPUTERS
EXCRETION
IBM COMPUTERS
METABOLISM
PHYSIOLOGY
RADIOISOTOPES
RENAL CLEARANCE
TRACER TECHNIQUES
CLEARANCE
ISOTOPE APPLICATIONS
ISOTOPES
MEDICINE
550601* - Medicine- Unsealed Radionuclides in Diagnostics
550901 - Pathology- Tracer Techniques
551001 - Physiological Systems- Tracer Techniques
990200 - Mathematics & Computers