Recombinant Brucella abortus gene expressing immunogenic protein
Patent
·
OSTI ID:5755016
This patent describes a synthetic recombinant DNA molecule containing a DNA sequence. It comprises a gene of Brucella abortus encoding an immunogenic protein having a molecular weight of approximately 31,000 daltons as determined by sodium dodecyl sulfate polyacrylamide gel electrophoresis under denaturing conditions, the protein having an isoelectric point around 4.9, and containing a twenty-five amino acid sequence from its amino terminal end consisting of Gln-Ala-Pro-Thr-Phe-Phe-Arg-Ile-Gly-Thr-Gly-Gly-Thr-Ala-Gly-Thr-Tyr-Tyr-Pro-Ile-Gly-Gly-Leu-Ile-Ala, wherein Gln, Ala, Pro, Thr, Phe, Arg, Ile, Gly, Tyr, and Leu, respectively, represent glutamine, alanine, proline, threonine, phenylalanine, arginine, isolecuine, glycine, tyrosine, and leucine.
- Assignee:
- Iowa State Univ. Research Foundation, Ames, IA (United States)
- Patent Number(s):
- US 5023174; A
- Application Number:
- PPN: US 7-365226
- OSTI ID:
- 5755016
- Country of Publication:
- United States
- Language:
- English
Similar Records
Novel human growth hormone like protein HGH-V encoded in the human genome
Amino-terminal sequences of the L,M, and H subunits of reaction centers from the photosynthetic bacterium Rhodopseudomonas sphaeroides R-26
Covalent structure of apolipoprotein A-II from Macaca mulatta serum high-density lipoproteins. [Apolipoprotein]
Patent
·
Tue May 12 00:00:00 EDT 1987
·
OSTI ID:6409756
Amino-terminal sequences of the L,M, and H subunits of reaction centers from the photosynthetic bacterium Rhodopseudomonas sphaeroides R-26
Journal Article
·
Thu Dec 31 23:00:00 EST 1981
· Biochemistry; (United States)
·
OSTI ID:6123793
Covalent structure of apolipoprotein A-II from Macaca mulatta serum high-density lipoproteins. [Apolipoprotein]
Journal Article
·
Mon Mar 22 23:00:00 EST 1976
· Biochemistry; (United States)
·
OSTI ID:7187547
Related Subjects
550400* -- Genetics
59 BASIC BIOLOGICAL SCIENCES
BACTERIA
BIOSYNTHESIS
BRUCELLA
COLLOIDS
DISPERSIONS
DNA
DNA SEQUENCING
ELECTROPHORESIS
GELS
GENE RECOMBINATION
GLOBULINS
IMMUNOGLOBULINS
IMMUNOLOGY
MICROORGANISMS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PHENOTYPE
PROTEIN ENGINEERING
PROTEINS
RECOMBINANT DNA
STRUCTURAL CHEMICAL ANALYSIS
SYNTHESIS
59 BASIC BIOLOGICAL SCIENCES
BACTERIA
BIOSYNTHESIS
BRUCELLA
COLLOIDS
DISPERSIONS
DNA
DNA SEQUENCING
ELECTROPHORESIS
GELS
GENE RECOMBINATION
GLOBULINS
IMMUNOGLOBULINS
IMMUNOLOGY
MICROORGANISMS
NUCLEIC ACIDS
ORGANIC COMPOUNDS
PHENOTYPE
PROTEIN ENGINEERING
PROTEINS
RECOMBINANT DNA
STRUCTURAL CHEMICAL ANALYSIS
SYNTHESIS