Measurement of tissue optical properties by the use of oblique-incidence optical fiber reflectometry
- Department of Electrical and Computer Engineering, Rice University, P.O. Box 1892, Houston, Texas 77251 (United States)
Fiber-optic-based oblique-incidence reflectometry is a simple and accurate method for measuring the absorption and reduced scattering coefficients {mu}{sub a} and {mu}{sub s}{prime} of semi-infinite turbid media. Obliquely incident light produces a spatial distribution of diffuse reflectance that is not centered about the point of light entry. The amount of shift in the center of diffuse reflectance is directly related to the medium{close_quote}s diffusion length D. We developed a fiber-optic probe to deliver light obliquely and sample the relative profile of diffuse reflectance. Measurement in absolute units is not necessary. From the profile, it was possible to measure D, perform a curve fit for the effective attenuation coefficient {mu}{sub eff}, and then calculate {mu}{sub a} and {mu}{sub s}{prime}. This method was verified with Monte Carlo simulations and tested on tissue phantoms. Our measurements of D and {mu}{sub eff} had an accuracy of approximately 5{percent}, thus giving us 10{percent} and 5{percent} accuracy for {mu}{sub a} and {mu}{sub s}{prime}, respectively. {copyright} 1997 Optical Society of America
- OSTI ID:
- 575174
- Journal Information:
- Applied Optics, Journal Name: Applied Optics Journal Issue: 1 Vol. 36; ISSN APOPAI; ISSN 0003-6935
- Country of Publication:
- United States
- Language:
- English
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