Beta-Irradiation of choroidal melanoma with /sup 106/Ru//sup 106/Rh applicators. 16 years' experience
From 1964 to 1980, 205 patients with choroidal melanoma were treated with /sup 106/Ru//sup 106/Rh beta-ray applicators (8,000 to 10,000 rad at the summit of the tumor within 14 days). In 132 (64.4%) cases, this treatment was successful. Thirty-six (17.6%) had to be enucleated after irradiation and 37 died, 21 of them of metastases. Of the 132 successfully treated patients, 60 (45.5%) had flat scars and 34 (25.8%) retained a visual acuity of 0.5 to 1.5. Radiogenic late complications with damage to the retinal capillary system were the main causes of visual deterioration, especially in eyes with tumors close to the posterior pole. The survival rate of 85.1% after five years is substantially higher than that for patients who were primarily treated with enucleation.
- Research Organization:
- Municipal Eye Hospital, Berlin
- OSTI ID:
- 5741903
- Journal Information:
- Arch. Ophthalmol. (Chicago); (United States), Vol. 101:5
- Country of Publication:
- United States
- Language:
- English
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EYES
BIOLOGICAL RADIATION EFFECTS
MELANOMAS
RADIOTHERAPY
SIDE EFFECTS
EVALUATION
PATIENTS
RHODIUM 106
RUTHENIUM 106
VISION
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
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BODY AREAS
DISEASES
EVEN-EVEN NUCLEI
FACE
HEAD
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
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NUCLEAR MEDICINE
NUCLEI
ODD-ODD NUCLEI
ORGANS
RADIATION EFFECTS
RADIOISOTOPES
RADIOLOGY
RHODIUM ISOTOPES
RUTHENIUM ISOTOPES
SECONDS LIVING RADIOISOTOPES
SENSE ORGANS
THERAPY
YEARS LIVING RADIOISOTOPES
560151* - Radiation Effects on Animals- Man
550603 - Medicine- External Radiation in Therapy- (1980-)