Thallium stress testing does not predict cardiovascular risk in diabetic patients with end-stage renal disease undergoing cadaveric renal transplantation

Journal Article · Wed May 01 00:00:00 EDT 1991 · American Journal of Medicine; (USA)

DOI:https://doi.org/10.1016/0002-9343(91)90630-G· OSTI ID:5733989

Holley, J L; Fenton, R A; Arthur, R S ^[1]

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1. Univ. of Pittsburgh, PA (USA)

This study assessed the usefulness of thallium stress testing as a predictor of perioperative cardiovascular risk in diabetic patients with end-stage renal disease undergoing cadaveric renal transplantation. Demographic factors influencing the exercise performance in these patients were also examined. The medical records of 189 consecutive patients with diabetic nephropathy who were evaluated for cadaveric renal transplantation were reviewed. Thallium stress testing was the initial examination of cardiovascular status in 141 patients. An adequate examination was one in which at least 70% of maximum heart rate was achieved. A thallium stress test was normal if there were no ST segment depressions on the electrocardiogram and no perfusion abnormalities on the thallium scan. Forty-four patients underwent cardiac catheterization as the initial evaluation (Group C) and four patients underwent transplantation without a formal cardiovascular evaluation (Group D). Sixty-four of the 141 patients undergoing thallium stress testing had an adequate and normal examination (Group A). The incidence of perioperative cardiac events in this group was 2%. Seventy-seven patients (Group B) had an abnormal (n = 41) or an inadequate (n = 36) thallium stress test and most (n = 61) then underwent coronary angiography. The use of beta-blockers was the only predictor of an abnormal or inadequate thallium stress test. Forty-three percent of patients with inadequate or abnormal thallium stress tests had significant coronary artery disease on cardiac catheterization. The perioperative risk of cardiac events was not different in Group A versus Groups B, C, and D combined. Survival of Group A and B patients was not different but was significantly longer than that of Group C patients.

• OSTI ID: 5733989
• Journal Information: American Journal of Medicine; (USA), Vol. 90:5; ISSN 0002-9343
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
CARDIOVASCULAR DISEASES
DIAGNOSIS
KIDNEYS
TRANSPLANTS
DIABETES MELLITUS
ELECTROCARDIOGRAMS
EXERCISE
FORECASTING
PATIENTS
RISK ASSESSMENT
THALLIUM 201
UROGENITAL SYSTEM DISEASES
BETA DECAY RADIOISOTOPES
BODY
DAYS LIVING RADIOISOTOPES
DIAGRAMS
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE DISEASES
HEAVY NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
METABOLIC DISEASES
NUCLEI
ODD-EVEN NUCLEI
ORGANS
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
THALLIUM ISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics