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Simulation of lifetime radon exposures using observation data

Conference · · Archives of Environmental Health; (USA)
OSTI ID:5733870
;  [1]
  1. Argonne National Laboratory, IL (USA)

The frequency distribution of lifetime risk of radon-induced lung cancer is a function of the frequency distribution of lifetime radon exposure, which differs from the frequency distribution of radon in homes because of residential mobility. Cumulative personal exposures are averages of a variable number of house radon values, weighted according to duration of occupancy and recency of residence. We simulated a distribution of individual, cumulative Working Level Month (WLM) exposures using observed residence histories from lung cancer cases from Eastern Pennsylvania and (basement) Working Levels (WL) from a survey of Reading Prong, Pennsylvania. The measurements for basement-level houses have a higher skewed distribution, well-approximated by a Gamma distribution with small shape parameter for this high-radon area, where 30% of the houses have basement radon levels that exceed 9 pCi/{ell}. Using the BEIR IV model and assuming a 50% occupancy factor, we assigned either lifetime residence in a single house or a real residence history at random for women randomly selected from the age distribution of female lung cancer cases. Averaging over houses reduces the exposure of the most highly exposed 5% of the population but increases it for 95%: the upper 25% attains lifetime exposure of {ge} 74 WLM, yielding a relative risk (RR) {ge} 2.1. Ignoring mobility and basing the calculations on the distribution of radon in houses, the corresponding values would be 48.0 WLM and a RR of 1.7. The 50th percentile of the population has an estimated WLM exposure of 34.6 (RR = 1.5); this estimate would be 16.8 (RR = 1.2) if we assume one house per lifetime.

OSTI ID:
5733870
Report Number(s):
CONF-890937--
Journal Information:
Archives of Environmental Health; (USA), Journal Name: Archives of Environmental Health; (USA) Vol. 45:5; ISSN 0003-9896; ISSN AEHLA
Country of Publication:
United States
Language:
English