Extraction procedure may not be feasible for cadmium analysis of tissues, such as horse kidney cortex, having a very high cadmium content

Journal Article · Tue Dec 01 04:00:00 EST 1981 · Bull. Environ. Contam. Toxicol.; (United States)

DOI:https://doi.org/10.1007/BF01611100· OSTI ID:5724643

Elinder, C G ^[1]; Lind, B; Piscator, M; Sundstedt, K; Akerberg, S

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1. The Karenlinska Inst., Stockholm, Sweden

In the light of the discrepancy between data on cadmium in horse kidney in the U.S. and what has been reported in Europe the present authors have tested the analytical procedure used by Penumarthy et al. (1980). Cadmium in reference pig kidney and horse kidney cortex was determined by flame atomic absorption spectrophotometry after wet digestion, dissolving of the residue in water, complexing with APDC and extraction into MIBK. The ratio between the measured amount (minus blank) and the calculated amount of cadmium in the samples was 86% for blank with addition of 0.5 ..mu..g cadmium and 91% for low-level pig kidney cortex with or without the addition of 0.5 ..mu..g cadmium. The ratio was unacceptably low for horse kidney cortex having a concentration of greater than or equal to 117 ..mu..g/g dry wt. Concentrations of this magnitude are also found in human kidney and in human and horse liver. Data of Penumarthy et al. (1980) are also unusual in that the average cadmium concentration was 3.4 ..mu..g/g wet wt in horse liver and 2.5 ..mu..g/g in horse kidney. As a rule, cadmium concentration in kidney exceeds that in liver by a factor of 2-15. The capacity of the extraction procedure appears to be insufficient at high and intermediate cadmium levels. 1 table (JMT)

• OSTI ID: 5724643
• Journal Information: Bull. Environ. Contam. Toxicol.; (United States), Journal Name: Bull. Environ. Contam. Toxicol.; (United States) Vol. 27:6; ISSN BECTA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400105* -- Separation Procedures
560305 -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BODY
CADMIUM
CHEMICAL ANALYSIS
COMPARATIVE EVALUATIONS
DATA
DIGESTIVE SYSTEM
DOMESTIC ANIMALS
ELEMENTS
EVALUATION
EXPERIMENTAL DATA
EXTRACTION
GLANDS
HORSES
INFORMATION
KIDNEYS
LIVER
MAMMALS
MEASURING METHODS
METALS
NUMERICAL DATA
ORGANS
QUANTITATIVE CHEMICAL ANALYSIS
SEPARATION PROCESSES
SWINE
VERTEBRATES