Convenient synthesis of alkyl amines via the reaction of organoboranes with ammonium hydroxide

Journal Article · Fri Oct 09 04:00:00 EDT 1981 · J. Org. Chem.; (United States)

DOI:https://doi.org/10.1021/jo00334a041· OSTI ID:5723917

Kabalka, G W; Sastry, K A.R.; McCollum, G W; Yoshioka, H

A process for the preparation of alkyl amines in which the reagents are generated in situ under mild and convenient reaction conditions is described. An organoborane is prepared via hydroboration, aqueous ammonium hydroxide is added, and then aqueous sodium hypochlorite is added to the mixture. Two of the alkyl groups in the trialkylborane are converted to the corresponding amines in good yield. (BLM)

• Research Organization: Univ. of Tennessee, Knoxville
• DOE Contract Number: AS05-80EV10363
• OSTI ID: 5723917
• Journal Information: J. Org. Chem.; (United States), Journal Name: J. Org. Chem.; (United States) Vol. 46:21; ISSN JOCEA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400301* -- Organic Chemistry-- Chemical & Physicochemical Properties-- (-1987)
ALKALI METAL COMPOUNDS
AMINES
AMMONIUM COMPOUNDS
AMMONIUM HYDROXIDES
AQUEOUS SOLUTIONS
BORANES
BORON COMPOUNDS
CHEMICAL PREPARATION
CHEMICAL REACTIONS
DISPERSIONS
HYDROGEN COMPOUNDS
HYDROXIDES
HYPOCHLOROUS ACID
INORGANIC ACIDS
MIXTURES
ORGANIC COMPOUNDS
ORGANOMETALLIC COMPOUNDS
OXYGEN COMPOUNDS
SODIUM COMPOUNDS
SOLUTIONS
SYNTHESIS