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Title: Prenatal methylmercury poisoning: clinical observations over five years

Abstract

Thirty-two infants prenatally exposed to methylmercury and their mothers were examined over a five-year period after the Iraqi methylmercury epidemic. Severity of poisoning in mothers was related to the peak mercury concentration in their hair and in the infants to the maximum concentration in maternal hair during pregnancy. In nine cases of cerebral palsy, methylmercury exposure occurred only during the last trimester. All infants except three (two were orphaned soon after birth and one was bottle-fed) were exposed postnatally via suckling. Whereas the mother's symptoms usually improved, the damage to the fetal nervous system appears to be permanent. Milder cases previously not identified in other studies are reported. The syndrome consists of varying degrees of developmental retardation in addition to exaggerated tendon reflexes and the pathologic extensor plantar reflex (minimal brain damage syndrome).

Authors:
 [1]; ; ; ; ;
  1. (Univ. of Baghdad, Iraq)
Publication Date:
OSTI Identifier:
5705445
Resource Type:
Journal Article
Journal Name:
Am. J. Dis. Child.; (United States)
Additional Journal Information:
Journal Volume: 133
Country of Publication:
United States
Language:
English
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; INFANTS; METHYLMERCURY; HEALTH HAZARDS; PREGNANCY; EPIDEMIOLOGY; IRAQ; NERVOUS SYSTEM DISEASES; TOXICITY; ANIMALS; ASIA; CHILDREN; DISEASES; HAZARDS; MAMMALS; MAN; MIDDLE EAST; NEONATES; ORGANIC COMPOUNDS; ORGANIC MERCURY COMPOUNDS; PRIMATES; VERTEBRATES; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987); 550600 - Medicine

Citation Formats

Amin-Zaki, L., Majeed, M.A., Elhassani, S.B., Clarkson, T.W., Greenwood, M.R., and Doherty, R.A. Prenatal methylmercury poisoning: clinical observations over five years. United States: N. p., 1979. Web. doi:10.1001/archpedi.1979.02130020064013.
Amin-Zaki, L., Majeed, M.A., Elhassani, S.B., Clarkson, T.W., Greenwood, M.R., & Doherty, R.A. Prenatal methylmercury poisoning: clinical observations over five years. United States. doi:10.1001/archpedi.1979.02130020064013.
Amin-Zaki, L., Majeed, M.A., Elhassani, S.B., Clarkson, T.W., Greenwood, M.R., and Doherty, R.A. Thu . "Prenatal methylmercury poisoning: clinical observations over five years". United States. doi:10.1001/archpedi.1979.02130020064013.
@article{osti_5705445,
title = {Prenatal methylmercury poisoning: clinical observations over five years},
author = {Amin-Zaki, L. and Majeed, M.A. and Elhassani, S.B. and Clarkson, T.W. and Greenwood, M.R. and Doherty, R.A.},
abstractNote = {Thirty-two infants prenatally exposed to methylmercury and their mothers were examined over a five-year period after the Iraqi methylmercury epidemic. Severity of poisoning in mothers was related to the peak mercury concentration in their hair and in the infants to the maximum concentration in maternal hair during pregnancy. In nine cases of cerebral palsy, methylmercury exposure occurred only during the last trimester. All infants except three (two were orphaned soon after birth and one was bottle-fed) were exposed postnatally via suckling. Whereas the mother's symptoms usually improved, the damage to the fetal nervous system appears to be permanent. Milder cases previously not identified in other studies are reported. The syndrome consists of varying degrees of developmental retardation in addition to exaggerated tendon reflexes and the pathologic extensor plantar reflex (minimal brain damage syndrome).},
doi = {10.1001/archpedi.1979.02130020064013},
journal = {Am. J. Dis. Child.; (United States)},
number = ,
volume = 133,
place = {United States},
year = {1979},
month = {2}
}