Quantitative computed tomographic evaluation of femoral bone mineral content in renal osteodystrophy compared with radial photon absorptiometry

Journal Article · Mon May 01 04:00:00 EDT 1989 · Invest. Radiol.; (United States)

DOI:https://doi.org/10.1097/00004424-198905000-00008· OSTI ID:5700663

Sakurai, K; Marumo, F; Iwanami, S; Uchida, H; Matsubayashi, T

The computed tomography (CT) numbers of cortical bone at the level of 20 cm (CT20) and of spongiosa in the lateral condyle at the level of 2 cm (CT02) from the distal end of the femur were obtained by a quantitative CT method and compared with the bone mineral density of mostly cortical bone within the radius (BMD) by photon absorptiometry. The study included 47 patients with chronic renal failure not dialyzed or induced to regular hemodialysis within 4 weeks of the study (group 1), 28 patients on regular hemodialysis for more than one month (group 2), and ten healthy volunteers (group 3). The measures of bone mineral content (BMC), namely CT20, CT02, and BMD, were compared in terms of their abilities to distinguish members in the various groups. For group 1 and group 3, the greatest variation in BMC was in the difference in CT02, which was primarily a measurement of the BMC of spongiosa. For groups 1 and 2, the greatest variation was in the difference in BMD, which was primarily a measurement of the BMC of cortex. The reproducibility of CT02 was estimated as almost equal to the difference in CT02 values at intervals of 10 months' duration of hemodialysis. The results indicated that CT02 was a useful measurement for evaluating the progress in the early stage of the renal osteodystrophy, and it is recommended that the bone mineral measurement with this QCT method should be performed once or twice a year.

• Research Organization: Kitasato Univ. School of Medicine, Kanagawa (Japan)
• OSTI ID: 5700663
• Journal Information: Invest. Radiol.; (United States), Journal Name: Invest. Radiol.; (United States) Vol. 24:5; ISSN INVRA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
DENSITY
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIALYSIS
DISEASES
EMISSION COMPUTED TOMOGRAPHY
FEMUR
KIDNEYS
MINERALS
ORGANS
PATIENTS
PHOTON EMISSION SCANNING
PHYSICAL PROPERTIES
SEPARATION PROCESSES
SKELETON
TOMOGRAPHY
UROGENITAL SYSTEM DISEASES