Stereotactic heavy-charged-particle Bragg peak radiosurgery for the treatment of intracranial arteriovenous malformations in childhood and adolescence
Journal Article
·
· Neurosurgery; (United States)
Forty patients aged 6 to 18 years have now been treated for inoperable intracranial arteriovenous malformations (AVMs) using stereotactic heavy-charged-particle Bragg peak radiosurgery at the Lawrence Berkeley Laboratory 184-inch Synchrocyclotron at the University of California, Berkeley. This paper describes the procedures for selection of patients, the treatment protocol, and the neurological and neuroradiological responses to stereotactic radiosurgery in this age group. The volumes of the treated AVMs ranged from 265 mm/sup 3/ to 60,000 mm/sup 3/. The results are favorable: thus far, 20 of 25 patients have experienced greater than or equal to 50% obliteration of their AVMs within 1 year after treatment, and 14 of 18 patients have experienced total obliteration of the AVM by 2 years after treatment. Two patients hemorrhaged from radiosurgically treated AVMs within 12 months after treatment, but none thereafter. Complications include vasogenic edema and arterial occlusion; three patients have had neurological worsening as definite or possible sequelae of treatment. The strengths and limitations of the method are discussed.
- Research Organization:
- Lawrence Berkeley Lab., CA (USA)
- OSTI ID:
- 5697673
- Journal Information:
- Neurosurgery; (United States), Journal Name: Neurosurgery; (United States) Vol. 24:6; ISSN NRSRD
- Country of Publication:
- United States
- Language:
- English
Similar Records
Clinical results of stereotactic heavy-charged-particle radiosurgery for intracranial angiographically occult vascular malformations
Clinical results of stereotactic heavy-charged-particles radiosurgery for intracranial arteriovenous malformations
Stereotactic helium-ion radiosurgery for the treatment of intracranial arteriovenous malformations
Conference
·
Thu Nov 30 23:00:00 EST 1989
·
OSTI ID:7001525
Clinical results of stereotactic heavy-charged-particles radiosurgery for intracranial arteriovenous malformations
Conference
·
Thu Nov 30 23:00:00 EST 1989
·
OSTI ID:7018394
Stereotactic helium-ion radiosurgery for the treatment of intracranial arteriovenous malformations
Conference
·
Thu Nov 30 23:00:00 EST 1989
·
OSTI ID:7105282