Factors modifying toxicity of ozone

Journal Article · Thu Jan 01 04:00:00 EST 1959 · Adv. Chem. Ser.; (United States)

DOI:https://doi.org/10.1021/ba-1959-0021.ch048· OSTI ID:5694543

Stokinger, H E

Ozone in single, acute exposure is a highly poisonous substance to laboratory animals. No experimental evidence was found that this toxicity is modified to a significant degree by the presence of nitrogen oxides that may accompany ozone production. Seven factors have been experimentally found that may modify the toxicity of ozone. Four of these youth, physical exertion, alcohol, and respiratory infection tend to augment the injurious response or act to the detriment of the host; intermittent exposure, premedication, and pre-exposure either reduce or eliminate the injurious effects of ozone. Consideration has been given these factors in the evaluation of possible hazards to populations from ozone-containing smogs.

• Research Organization: Dept. of Health, Education, and Welfare, Cincinnati, OH
• OSTI ID: 5694543
• Journal Information: Adv. Chem. Ser.; (United States), Journal Name: Adv. Chem. Ser.; (United States) Vol. 21; ISSN ADCSA
• Country of Publication: United States
• Language: English

Related Subjects

500200 -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACUTE EXPOSURE
BIOLOGICAL EFFECTS
CHALCOGENIDES
HAZARDS
HEALTH HAZARDS
NITROGEN COMPOUNDS
NITROGEN OXIDES
OXIDES
OXYGEN COMPOUNDS
OZONE
RESPONSE MODIFYING FACTORS
RISK ASSESSMENT
SMOG
TOXICITY