Radiotherapy for primary brain tumors in very young children

Journal Article · Wed Dec 15 00:00:00 EST 1982 · Cancer (Philadelphia); (United States)

DOI:https://doi.org/10.1002/1097-0142(19821215)50:12<2785::AID-CNCR2820501216>3.0.CO;2-7· OSTI ID:5683781

Deutsch, M

Ninety-one children younger than age five years have been treated with radiotherapy for primary intracranial tumors. Patients with cerebellar astrocytomas and optic chiasm gliomas did relatively well, whereas brain stem tumors, extensive posterior fossa tumors and cerebral gliomas had a poor prognosis. Medulloblastomas, ependymomas, and midbrain tumors were of intermediate prognosis. There was no definite correlation between age at diagnosis and survival, although patients over 24 months of age seemed to do sightly better. Tumor doses of at least 4000 rad seem necessary for any likelihood of control. Of 63 children diagnosed over five years ago, 27(43%) survived at least five years. The majority of long-term survivors are leading normal lives, although many have mild impairments.

• Research Organization: Univ. Health Center of Pittsburgh, PA
• OSTI ID: 5683781
• Journal Information: Cancer (Philadelphia); (United States), Vol. 50:12
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BRAIN
FRACTIONATED IRRADIATION
NEOPLASMS
RADIOTHERAPY
SIDE EFFECTS
SPINAL CORD
BIOLOGICAL RADIATION EFFECTS
CHILDREN
SURVIVAL TIME
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DISEASES
IRRADIATION
MEDICINE
NERVOUS SYSTEM
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
THERAPY
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