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Title: Pulmonary cytomegalovirus infection: detection by Gallium-67 imaging in the transplant patient

Journal Article · · Arch. Intern. Med.; (United States)

Cytomegalovirus (CMV) infection is a frequent complication during the first few months following renal transplantation. The diagnosis is sometimes difficult but may be made by viral culture, a fourfold rise in the CMV antibody titer, or by demonstration of the CMV inclusions in the affected tissue. An increased pulmonary uptake of gallium citrate Ga 67 has been demonstrated following renal transplantation in two patients, each of whom had a fourfold rise in CMV complement fixing antibody titer, one of whom additionally had CMV inclusion bodies in a lung biopsy specimen prior to clinical or radiological demonstration of the pulmonary involvement. Gallium imaging, therefore, appears to be a valuable noninvasive test for early diagnosis of CMV pulmonary infections.

Research Organization:
Univ. of Oklahoma, Oklahoma City
OSTI ID:
5674070
Journal Information:
Arch. Intern. Med.; (United States), Vol. 139:3
Country of Publication:
United States
Language:
English