Pulmonary cytomegalovirus infection: detection by Gallium-67 imaging in the transplant patient

Journal Article · Thu Mar 01 04:00:00 EST 1979 · Arch. Intern. Med.; (United States)

DOI:https://doi.org/10.1001/archinte.139.3.286· OSTI ID:5674070

Hamed, I A; Wenzl, J E; Leonard, J C; Altshuler, G P; Pederson, J A

Cytomegalovirus (CMV) infection is a frequent complication during the first few months following renal transplantation. The diagnosis is sometimes difficult but may be made by viral culture, a fourfold rise in the CMV antibody titer, or by demonstration of the CMV inclusions in the affected tissue. An increased pulmonary uptake of gallium citrate Ga 67 has been demonstrated following renal transplantation in two patients, each of whom had a fourfold rise in CMV complement fixing antibody titer, one of whom additionally had CMV inclusion bodies in a lung biopsy specimen prior to clinical or radiological demonstration of the pulmonary involvement. Gallium imaging, therefore, appears to be a valuable noninvasive test for early diagnosis of CMV pulmonary infections.

• Research Organization: Univ. of Oklahoma, Oklahoma City
• OSTI ID: 5674070
• Journal Information: Arch. Intern. Med.; (United States), Journal Name: Arch. Intern. Med.; (United States) Vol. 139:3; ISSN AIMDA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACID SALTS
CITRATES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM COMPOUNDS
GALLIUM ISOTOPES
INFECTIOUS DISEASES
INTERMEDIATE MASS NUCLEI
ISOTOPES
KIDNEYS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM DISEASES
SCINTISCANNING
SIDE EFFECTS
TRANSPLANTS
VIRAL DISEASES