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Determinants of perioperative morbidity and mortality after pneumonectomy

Journal Article · · Annals of Thoracic Surgery; (USA)
; ; ; ; ; ;  [1]
  1. Univ. of Texas, M.D. Anderson Cancer Center, Houston (USA)

A total of 197 consecutive patients undergoing pneumonectomy at the M.D. Anderson Cancer Center from 1982 to 1987 were reviewed. Sixty-five variables were analyzed for the predictive value for perioperative risk. The operative mortality rate was 7% (14/197). Patients having a right pneumonectomy (n = 95) had a higher operative mortality rate (12%) than patients having a left pneumonectomy (1%, p less than 0.05). The extent of resection correlated with the operative mortality rate (chest wall resection or extrapleural pneumonectomy, n = 39, 15%; versus simple or intrapericardial pneumonectomy, n = 158, 5%; p less than 0.05). Patients whose predicted postoperative pulmonary function, by spirometry and xenon 133 regional pulmonary function studies, was a forced expiratory volume in 1 second greater than 1.65 L, forced expiratory volume in 1 second greater than 58% of the preoperative value, forced vital capacity greater than 2.5 L, or forced vital capacity greater than 60% of the preoperative value had a lower operative mortality rate (p less than 0.05). Atrial arrhythmia was the most common postoperative complication (23%). Xenon 133 regional pulmonary function studies are useful in predicting the risks of pneumonectomy.

OSTI ID:
5671230
Journal Information:
Annals of Thoracic Surgery; (USA), Journal Name: Annals of Thoracic Surgery; (USA) Vol. 48:1; ISSN 0003-4975; ISSN ATHSA
Country of Publication:
United States
Language:
English