Radioimmunoassay of bone morphogenetic protein in serum: a tissue-specific parameter of bone metabolism

Journal Article · Tue May 01 00:00:00 EDT 1984 · Proc. Soc. Exp. Biol. Med.; (United States)

DOI:https://doi.org/10.3181/00379727-176-41900· OSTI ID:5665344

Urist, M R; Hudak, R T

Bone morphogenetic protein (BMP), a paracrine agent inducing cartilage and bone cell differentiation, circulates in the blood and is detectable by BMP radioimmunoassay. Serum BMP levels are higher in growing children and patients with Paget's disease than in normal adults. These observations are interpreted as evidence of a BMP function in the physiology of bone in health and disease.

• Research Organization: Univ. of California, Los Angeles
• OSTI ID: 5665344
• Journal Information: Proc. Soc. Exp. Biol. Med.; (United States), Vol. 176:1
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BONE TISSUES
METABOLISM
PROTEINS
RADIOIMMUNOASSAY
SKELETAL DISEASES
DIAGNOSIS
BLOOD SERUM
CELL DIFFERENTIATION
CHILDREN
PATIENTS
AGE GROUPS
ANIMAL TISSUES
BODY
CONNECTIVE TISSUE
DISEASES
ISOTOPE APPLICATIONS
ORGANIC COMPOUNDS
RADIOASSAY
TISSUES
TRACER TECHNIQUES
550601* - Medicine- Unsealed Radionuclides in Diagnostics