Toxic and genetic effects of fuel oil photoproducts and three hydroperoxides in Saccharomyces cerevisiae

Journal Article · Fri Sep 01 04:00:00 EDT 1978 · J. Toxicol. Environ. Health; (United States)

DOI:https://doi.org/10.1080/15287397809529711· OSTI ID:5653879

Callen, D F; Larson, R A

Phototransformation of no. 2 fuel oil by UV irradiation at wavelengths designed to simulate sunlight resulted in the formation of products toxic to the yeast Saccharomyces cerevisiae. Increasing the time of irradiation of the fuel oil samples increased the toxicity. Fuel oil that had been irradiated for 12 or 24 h was convertagenic to the yeast strain D4. The toxicity and genetic activity of these samples could be removed by treatment with thiacyclohexane. It is thought that hydroperoxides are the primary photoproducts responsible for these biological effects. Of three hydroperoxides tested, tert-butyl was convertagenic and cumene and tetralin were not. However, all three hydroperoxides were toxic to yeast.

• Research Organization: National Inst. of Environmental Health Sciences, Research Triangle Park, NC
• OSTI ID: 5653879
• Journal Information: J. Toxicol. Environ. Health; (United States), Journal Name: J. Toxicol. Environ. Health; (United States) Vol. 4:5-6; ISSN JTEHD
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
CHEMICAL REACTIONS
DECOMPOSITION
ELECTROMAGNETIC RADIATION
FUEL OILS
FUELS
FUNGI
GENETIC EFFECTS
GENETIC RADIATION EFFECTS
LIQUID FUELS
MICROORGANISMS
OILS
ORGANIC COMPOUNDS
OTHER ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
PEROXIDES
PETROLEUM PRODUCTS
PHOTOCHEMICAL REACTIONS
PHOTOLYSIS
PLANTS
RADIATION EFFECTS
RADIATIONS
SACCHAROMYCES
SACCHAROMYCES CEREVISIAE
TOXICITY
ULTRAVIOLET RADIATION
YEASTS