Marked increase of calcium uptake in the ATP-depleted red cells of patients with iron deficiency

Journal Article · Wed May 01 00:00:00 EDT 1985 · Am. J. Hematol.; (United States)

DOI:https://doi.org/10.1002/ajh.2830190108· OSTI ID:5641289

Shimoda, M; Yawata, Y

Calcium (Ca) uptake was markedly increased in ATP-depleted red cells of patients with iron deficiency anemia (IDA) compared to ATP- depleted normal red cells. The extent of increased Ca uptake was related to the severity of iron deficiency as judged by decreased mean cell volume. Moreover, the increased Ca uptake returned to normal levels after oral iron supplementation therapy. The net calcium content of fresh red cells from iron-deficient individuals was the same as in red cells from normal subjects. Sodium influx and ferric ion uptake appeared to be virtually unaffected in the iron deficient red cells.

• Research Organization: Kawasaki Medical School, Kurashiki, Japan
• OSTI ID: 5641289
• Journal Information: Am. J. Hematol.; (United States), Journal Name: Am. J. Hematol.; (United States) Vol. 19:1; ISSN AJHED
• Country of Publication: United States
• Language: English

Related Subjects

560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ALKALI METALS
ALKALINE EARTH METALS
ANEMIAS
ATP
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CALCIUM
DISEASES
ELEMENTS
ERYTHROCYTES
HEMIC DISEASES
IRON
MATERIALS
METALS
NUCLEOTIDES
NUTRITIONAL DEFICIENCY
ORGANIC COMPOUNDS
PATIENTS
SODIUM
SYMPTOMS
TRANSITION ELEMENTS
UPTAKE