Iodine 131 metaiodobenzylguanidine scintigraphy of medullary carcinoma of the thyroid
- Univ. of Florida School of Medicine, Jacksonville (USA)
We have presented a case of sporadic medullary carcinoma of the thyroid with documentation of localization of tracer {sup 131}I-MIBG within the primary neoplasm. A review of the nuclear medicine literature of localization techniques for MCT demonstrates that {sup 131}I-MIBG, while an excellent choice for diagnosis of pheochromocytoma and neuroblastoma, produces low yield and unpredictable concentration in other neural crest apudomas, including MCT. A low incidence of true-positive results with {sup 131}I-MIBG uptake and a high incidence of false-negative results make this radiopharmaceutical a suboptimal choice for diagnostic studies, but a potentially promising one as a therapeutic agent.33 references.
- OSTI ID:
- 5638808
- Journal Information:
- Southern Medical Journal; (USA), Vol. 84:5; ISSN 0038-4348
- Country of Publication:
- United States
- Language:
- English
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BETA-MINUS DECAY RADIOISOTOPES
BODY
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550601* - Medicine- Unsealed Radionuclides in Diagnostics