Progress report on hot particle studies
- Brookhaven National Lab., Upton NY (United States)
NCRP Report 106 on the effects of hot particles on the skin of pigs, monkeys, and humans was critically reviewed and reassessed. The analysis of the data of Forbes and Mikhail on the effects from activated UC{sub 2} particles, ranging in diameter from 144 {mu}m to 328 {mu}m, led to the formulation of a new model to predict both the threshold for acute ulceration and for ulcer diameter. In this model, a point dose of 27 Gy at a depth of 1.33 mm in tissue will cause an ulcer with a diameter determined by the radius to which this dose extends. Application of the model to the Forbes and Mikhail data obtained with mixed fission product beta particles yielded a threshold'' (5% probability) of 6 {times} 10{sup 9} beta particles from a point source of high energy (2.25 MeV maximum) beta particles on skin. The above model was used to predict that approximately 1.2 {times} 10{sup 10} beta particles from Sr-Y-90 would produce similar effects, since few Sr-90 beta particles reach 1.33 mm depth. These emissions correspond to doses at 70-{mu}m depth in tissue of approximately 5.3 to 5.5 Gy averaged over 1 cm{sup 2}, respectively.
- Research Organization:
- Nuclear Regulatory Commission, Washington, DC (United States). Div. of Regulatory Applications; Brookhaven National Lab., Upton, NY (United States)
- Sponsoring Organization:
- USNRC; Nuclear Regulatory Commission, Washington, DC (United States)
- DOE Contract Number:
- AC02-76CH00016
- OSTI ID:
- 5619491
- Report Number(s):
- NUREG/CR-5725; BNL-NUREG-52287; ON: TI92008637
- Country of Publication:
- United States
- Language:
- English
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61 RADIATION PROTECTION AND DOSIMETRY
SKIN
BIOLOGICAL RADIATION EFFECTS
DOSE-RESPONSE RELATIONSHIPS
DOSIMETRY
HUMAN POPULATIONS
MONKEYS
PROGRESS REPORT
RADIATION DOSES
REGRESSION ANALYSIS
STRONTIUM 90
SWINE
ULCERS
ALKALINE EARTH ISOTOPES
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BODY
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DOMESTIC ANIMALS
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EVEN-EVEN NUCLEI
INTERMEDIATE MASS NUCLEI
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MAMMALS
MATHEMATICS
NUCLEI
ORGANS
PATHOLOGICAL CHANGES
POPULATIONS
PRIMATES
RADIATION EFFECTS
RADIOISOTOPES
STATISTICS
STRONTIUM ISOTOPES
VERTEBRATES
YEARS LIVING RADIOISOTOPES
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