Cerebral blood flow and brain atrophy correlated by xenon contrast CT scanning

Journal Article · Fri Nov 01 04:00:00 EST 1985 · Comput. Radiol.; (United States)

DOI:https://doi.org/10.1016/0730-4862(85)90117-9· OSTI ID:5618876

Kitagawa, Y; Meyer, J S; Tanahashi, N; Rogers, R L; Tachibana, H; Kandula, P; Dowell, R E; Mortel, K F

Correlations between cerebral blood flow (CBF) measured during stable xenon contrast CT scanning and standard CT indices of brain atrophy were investigated in the patients with senile dementia of Alzheimer type, multi-infarct dementia and idiopathic Parkinson's disease. Compared to age-matched normal volunteers, significant correlations were found in patients with idiopathic Parkinson's disease between cortical and subcortical gray matter blood flow and brain atrophy estimated by the ventricular body ratio, and mild to moderate brain atrophy were correlated with stepwise CBF reductions. However, in patients with senile dementia of Alzheimer type and multi-infarct dementia, brain atrophy was not associated with stepwise CBF reductions. Overall correlations between brain atrophy and reduced CBF were weak. Mild degrees of brain atrophy are not always associated with reduced CBF.

• Research Organization: Veterans Administration Medical Center, Houston, TX
• OSTI ID: 5618876
• Journal Information: Comput. Radiol.; (United States), Journal Name: Comput. Radiol.; (United States) Vol. 6; ISSN COMRD
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ATROPHY
BLOOD FLOW
BODY
BRAIN
CAT SCANNING
CENTRAL NERVOUS SYSTEM
COMPUTERIZED TOMOGRAPHY
CORRELATIONS
DIAGNOSTIC TECHNIQUES
DISEASES
ELEMENTS
FLUIDS
GASES
NERVOUS SYSTEM
NERVOUS SYSTEM DISEASES
NONMETALS
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
RARE GASES
TOMOGRAPHY
XENON