Esophageal fistula associated with intracavitary irradiation for esophageal carcinoma

Journal Article · Thu May 01 04:00:00 EDT 1986 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.159.2.3961189· OSTI ID:5618251

Hishikawa, Y; Tanaka, S; Miura, T

Fifty-three patients with esophageal carcinoma were treated with high-dose-rate intracavitary irradiation following external irradiation. Ten patients developed esophageal fistula. Perforations were found in the bronchus (four), major vessels (four), pericardium (one), and mediastinum (one). The frequency of fistula occurrence in these patients was not remarkably different from that in 30 other patients treated only with greater than or equal to 50 Gy external irradiation. From the time of the development of esophageal fistula, intracavitary irradiation did not seem to accelerate the development of fistula. The fistulas in our ten patients proved to be associated with tumor, deep ulcer (created before intracavitary irradiation), chemotherapy, infection, and trauma rather than the direct effect of intracavitary irradiation.

• Research Organization: Hyogo College of Medicine, Japan
• OSTI ID: 5618251
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 2; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

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560151 -- Radiation Effects on Animals-- Man
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
DOSES
ESOPHAGUS
FISTULAE
INJURIES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
THERAPY