Relation between water solubility, octanol/water partition coefficients, and bioconcentration of organic chemicals in fish: a review
Journal Article
·
· Regul. Toxicol. Pharmacol.; (United States)
A survey was made of the literature describing relations between water solubility (S), the octanol-water partition coefficient (Poct), and the bioconcentration factor (BCF) of organic chemicals. Based on the relations between BCF and Poct it can be concluded that mostly BCF is log BCF = 0.79 log Poct-0.40. From relations between Poct and S it can be concluded that for most organic chemicals log Poct will not exceed 3 if S is greater than ca. 3 mmol/liter. This limit is far more reliable than the value of 2000 mg/liter which has been proposed by OECD Experts and confirmed by other authors.43 references.
- Research Organization:
- National Institute of Public Health and Environmental Hygiene, Bilthoven, The Netherlands
- OSTI ID:
- 5615434
- Journal Information:
- Regul. Toxicol. Pharmacol.; (United States), Vol. 4
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL AVAILABILITY
CORRELATIONS
ORGANIC COMPOUNDS
FISHES
OCTANOLS
SOLUBILITY
WATER
ALCOHOLS
ANIMALS
AQUATIC ORGANISMS
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
OXYGEN COMPOUNDS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology
BIOLOGICAL AVAILABILITY
CORRELATIONS
ORGANIC COMPOUNDS
FISHES
OCTANOLS
SOLUBILITY
WATER
ALCOHOLS
ANIMALS
AQUATIC ORGANISMS
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
OXYGEN COMPOUNDS
VERTEBRATES
560300* - Chemicals Metabolism & Toxicology