Lack of ozone effects on oxygen hemoglobin affinity

Journal Article · Tue May 01 00:00:00 EDT 1979 · Arch. Environ. Health; (United States)

DOI:https://doi.org/10.1080/00039896.1979.10667389· OSTI ID:5615415

Ross, B K; Hlastala, M P; Frank, R

Ozone exposure has been shown to cause erythrocyte damage and thus may be affecting oxygen delivery by the red cell. Oxyhemoglogin affinity, heme-oxygen binding site interaction (Hill coefficient), and red cell 2,3-diphosphogly-cerate concentrations were measured in a total of twenty-two New Zealand white rabbits exposed to ozone. Ozone exposures of 1 and 3 ppM for 4 hr in rabbits had no significant (P > .05) effect, immediate or delayed, on the parameters measured.

• Research Organization: Univ. of Washington, Seattle
• OSTI ID: 5615415
• Journal Information: Arch. Environ. Health; (United States), Vol. 34:3
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
59 BASIC BIOLOGICAL SCIENCES
OZONE
BIOLOGICAL EFFECTS
AIR POLLUTION
CHEMICAL BONDS
ERYTHROCYTES
HEME
HEMOGLOBIN
INHALATION
OXYGEN
RABBITS
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOXYLIC ACIDS
CRYOGENIC FLUIDS
ELEMENTS
FLUIDS
GLOBIN
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
INTAKE
MAMMALS
MATERIALS
NONMETALS
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PIGMENTS
POLLUTION
PORPHYRINS
PROTEINS
VERTEBRATES
560305* - Chemicals Metabolism & Toxicology- Vertebrates- (-1987)
550200 - Biochemistry