Triplex DNA finally comes of age
Journal Article
·
· Science (Washington, D.C.); (United States)
Researchers in several labs are exploring the use of triplex DNA to produce a new type of molecular scissors for cutting DNA. Even the best of the restriction enzymes that are currently used for that purpose cut at many sites, mincing the genome into a multitude of small bits that are hard to separate and analyze. But triplex-based scissors may be able to cut at one or a few sites, giving a much more manageable collection of large DNA pieces. Such scissors would be a great help in mapping and sequencing the human genome and in isolating individual genes.
- OSTI ID:
- 5603495
- Journal Information:
- Science (Washington, D.C.); (United States), Vol. 252:5011; ISSN 0036-8075
- Country of Publication:
- United States
- Language:
- English
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