Major intestinal complications of radiotherapy. Management and nutrition
Journal Article
·
· Arch. Surg. (Chicago); (United States)
Hospitalization was required in 57 patients for intestinal injuries following radiotherapy for carcinoma of the cervix, endometrium, ovary, bladder, rectum, and other primary sites. Intestinal complications included stenosis, perforation, rectal ulcer, and rectovaginal, ileovaginal, and ileovesical fistula; 27 patients had multiple intestinal complications. Operation was necessary in 33 patients, as follows: bowel resections, 18; colostomy alone, five; adhesiolysis, five; ileocolic bypass, three; and Hartmann's procedure for sigmoid perforation, two. Five anastomotic leaks and six postoperative deaths occurred. Causes of death among the remaining patients included residual cancer (ten), de novo bowel cancer (two), radiation injury (four), and unrelated causes (six). Resection to uninvolved bowel, omental wrap of anterior resection anastomosis, avoidance of unnecessary adhesiolysis, and long-tube orientation seemed to contribute to successful operations. Nutritional support was used for repletion, post-operative fistulas, and short-gut syndrome.
- Research Organization:
- Univ. of Toronto, Ontario
- OSTI ID:
- 5602817
- Journal Information:
- Arch. Surg. (Chicago); (United States), Journal Name: Arch. Surg. (Chicago); (United States) Vol. 122:12; ISSN ARSUA
- Country of Publication:
- United States
- Language:
- English
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560151* -- Radiation Effects on Animals-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
FEMALE GENITALS
GASTROINTESTINAL TRACT
GONADS
INJURIES
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LARGE INTESTINE
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OVARIES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
UTERUS
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
BODY
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
FEMALE GENITALS
GASTROINTESTINAL TRACT
GONADS
INJURIES
INTESTINES
LARGE INTESTINE
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
OVARIES
PATIENTS
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
RECTUM
SIDE EFFECTS
THERAPY
URINARY TRACT
UTERUS