Major intestinal complications of radiotherapy. Management and nutrition
Hospitalization was required in 57 patients for intestinal injuries following radiotherapy for carcinoma of the cervix, endometrium, ovary, bladder, rectum, and other primary sites. Intestinal complications included stenosis, perforation, rectal ulcer, and rectovaginal, ileovaginal, and ileovesical fistula; 27 patients had multiple intestinal complications. Operation was necessary in 33 patients, as follows: bowel resections, 18; colostomy alone, five; adhesiolysis, five; ileocolic bypass, three; and Hartmann's procedure for sigmoid perforation, two. Five anastomotic leaks and six postoperative deaths occurred. Causes of death among the remaining patients included residual cancer (ten), de novo bowel cancer (two), radiation injury (four), and unrelated causes (six). Resection to uninvolved bowel, omental wrap of anterior resection anastomosis, avoidance of unnecessary adhesiolysis, and long-tube orientation seemed to contribute to successful operations. Nutritional support was used for repletion, post-operative fistulas, and short-gut syndrome.
- Research Organization:
- Univ. of Toronto, Ontario
- OSTI ID:
- 5602817
- Journal Information:
- Arch. Surg. (Chicago); (United States), Vol. 122:12
- Country of Publication:
- United States
- Language:
- English
Similar Records
Radiation injury of the rectum: Evaluation of surgical treatment
Radiation injury of the rectum: evaluation of surgical treatment
Related Subjects
CARCINOMAS
RADIOTHERAPY
SIDE EFFECTS
BIOLOGICAL RADIATION EFFECTS
BLADDER
INTESTINES
OVARIES
PATIENTS
RADIATION INJURIES
RECTUM
UTERUS
BIOLOGICAL EFFECTS
BODY
DIGESTIVE SYSTEM
DISEASES
FEMALE GENITALS
GASTROINTESTINAL TRACT
GONADS
INJURIES
LARGE INTESTINE
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
RADIATION EFFECTS
RADIOLOGY
THERAPY
URINARY TRACT
560151* - Radiation Effects on Animals- Man