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U.S. Department of Energy
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Triterpenoid biosynthesis in Euphorbia lathyris latex

Thesis/Dissertation ·
OSTI ID:5600690

The structures of those tetracyclic triterpenols in Euphorbia lathyris latex which had not previously been known were elucidated. Many times dependent incubations were done, investigating the stability of the whole latex system and the re-suspended pellet systems. The effects of centrifugation on the biosynthesis were examined. The partitioning of the triterpenoid pool as a function of when the compounds were made was examined. A number of incubations were performed in the hopes of observing some interconversion of the individual triterpenols. The effect of several inhibitors on the biosynthesis of the triterpenoids was examined. The effects of the morpholine based fungicides, tridemorph and fenpropimorph were examined. The possibility that cycloartenol is made via lanosterol was investigated by synthesizing 4-R-4-{sup 3} H-mevalonic acid and incubating the latex with a mixture of this and {sup 14}C-mevalonic acid.

Research Organization:
California Univ., Berkeley, CA (USA)
OSTI ID:
5600690
Country of Publication:
United States
Language:
English