Phytotoxins from the pathogenic fungi Drechslera maydis and Drechslera sorghicola

Journal Article · Fri May 01 04:00:00 EDT 1987 · Proc. Natl. Acad. Sci. U.S.A.; (United States)

DOI:https://doi.org/10.1073/pnas.84.10.3081· OSTI ID:5597718

Sugawara, F; Strobel, G; Strange, R N; Siedow, J N; van Duyne, G D; Clardy, J

Drechslera maydis, the causal agent of Southern corn leaf blight, and Drechslera sorghicola, the causal agent of leaf spot on Johnson grass, produce a series of phytotoxic sesterterpenoids. These sesterterpenoids belong to the ophiobolin family. One of them, ophiobolin I, was characterized by x-ray diffraction and served as a crucial reference compound for characterizing four other ophiobolins. All of the ophiobolins studied produce characteristic lesions on host plants at concentrations of 1 mM to 1 ..mu..M. The ophiobolin characterized as 6-epiophiobolin A is selectively toxic to corn bearing Texas-male-sterile (Tms) cytoplasm when assayed in a dark CO/sub 2/ fixation assay. It is plausible that these ophiobolins had a role in the 1970 corn-blight epidemic in North America.

• Research Organization: Montana State Univ., Bozeman
• OSTI ID: 5597718
• Journal Information: Proc. Natl. Acad. Sci. U.S.A.; (United States), Journal Name: Proc. Natl. Acad. Sci. U.S.A.; (United States) Vol. 84:10; ISSN PNASA
• Country of Publication: United States
• Language: English

Related Subjects

550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ANTIGENS
CEREALS
COHERENT SCATTERING
DIFFRACTION
DISEASES
FEDERAL REGION VI
FUNGAL DISEASES
FUNGI
GRASS
INFECTIOUS DISEASES
LEAVES
MAIZE
MATERIALS
NORTH AMERICA
PATHOGENS
PLANTS
SCATTERING
STRUCTURAL CHEMICAL ANALYSIS
TEXAS
TOXIC MATERIALS
TOXINS
USA
X-RAY DIFFRACTION