(2- 14C)deoxyglucose uptake in rat visual system during flashing-diffuse and flashing-pattern stimulation over a 6 log range of luminance

Journal Article · Mon Jul 01 04:00:00 EDT 1991 · Experimental Neurology; (United States)

DOI:https://doi.org/10.1016/0014-4886(91)90149-7· OSTI ID:5595239

Cooper, R M; Thurlow, G A ^[1]

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1. Psychology Department, University of Calgary, Alberta (Canada)

The 2-deoxyglucose autoradiographic technique was used to assess the metabolic activity of cortical area 17, the dorsal and ventral lateral geniculate nuclei, the lateral posterior nucleus, and the superior colliculus, during 5-Hz flashing-pattern (montage of black and white square-wave gratings) and flashing-diffuse (eye covered with white mask) stimulation at three intensities over a 6 log range. In area 17 flashing-pattern was found to be equally effective at elevating uptake of the functional label over the photopic-scotopic range of luminance levels tested, whereas flashing-diffuse was ineffective. In subcortical nuclei, however, flashing-diffuse was no less effective than flashing-pattern and uptake of the label correlated positively with intensity level. The results suggest that the subcortical components of the visual system do play an important role in the processing of intensity information and that primary visual cortex does not.

• OSTI ID: 5595239
• Journal Information: Experimental Neurology; (United States), Journal Name: Experimental Neurology; (United States) Vol. 113:1; ISSN 0014-4886; ISSN EXNEA
• Country of Publication: United States
• Language: English

Related Subjects

550501* -- Metabolism-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALDEHYDES
ANIMALS
AUTORADIOGRAPHY
CARBOHYDRATES
CARBON 14 COMPOUNDS
CARBON COMPOUNDS
ELECTROMAGNETIC RADIATION
GLUCOSE
HEXOSES
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
METABOLISM
MONOSACCHARIDES
ORGANIC COMPOUNDS
RADIATIONS
RATS
RODENTS
SACCHARIDES
TRACER TECHNIQUES
VERTEBRATES
VISIBLE RADIATION