An autoradiographic map of (3H)diprenorphine binding in rat brain: effects of social interaction

Journal Article · Thu Oct 01 00:00:00 EDT 1981 · Brain Res. Bull.; (United States)

DOI:https://doi.org/10.1016/0361-9230(81)90038-1· OSTI ID:5589449

Panksepp, J; Bishop, P

(3H)Diprenorphine binding was analyzed autoradiographically in the brains of 33 day old rat pups. A photographic atlas of diprenorphine binding in the coronal plane is provided to highlight the dispersion of opioid receptor systems through the brain. To determine whether brain opioid release may be induced by social interactions, half the animals were sacrificed following a 30 min period of social interaction while the other half were sacrificed following 30 min of social isolation. Opioid binding was higher in isolate-tested animals than socially-tested ones, suggesting that social interaction may promote endogenous brain opioid release.

• Research Organization: Department of Psychology, Bowling Green State University, OH
• OSTI ID: 5589449
• Journal Information: Brain Res. Bull.; (United States), Vol. 7:4
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
BRAIN
AUTORADIOGRAPHY
TRITIUM COMPOUNDS
ISOTOPE APPLICATIONS
BEHAVIOR
BIOCHEMICAL REACTION KINETICS
BIOCHEMISTRY
RATS
RECEPTORS
SOCIOLOGY
ANIMALS
BODY
CENTRAL NERVOUS SYSTEM
CHEMISTRY
KINETICS
LABELLED COMPOUNDS
MAMMALS
NERVOUS SYSTEM
ORGANS
REACTION KINETICS
RODENTS
VERTEBRATES
550201* - Biochemistry- Tracer Techniques
550101 - Behavioral Biology- Tracer Techniques