Effects of external beam radiotherapy on endocrine function in patients with carcinoma of the prostate

Journal Article · Mon Mar 31 23:00:00 EST 1986 · J. Urol.; (United States)

OSTI ID:5587695

Grigsby, P W; Perez, C A

Serum levels of testosterone, dihydrotestosterone, and follicle-stimulating and luteinizing hormones were determined prospectively in 59 patients with carcinoma of the prostate treated curatively with external beam radiotherapy. Hormone levels were determined before the initiation of therapy and up to 2 years following completion of therapy. Testosterone levels remained unchanged but dihydrotestosterone levels decreased slightly. Follicle-stimulating and luteinizing hormone levels increased significantly during therapy and remained elevated for up to 2 years after therapy. These findings are consistent with low dose irradiation of the testis.

• Research Organization: Washington Univ. School of Medicine, St. Louis, MO
• OSTI ID: 5587695
• Journal Information: J. Urol.; (United States), Journal Name: J. Urol.; (United States) Vol. 4; ISSN JOURA
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
ANDROGENS
ANDROSTANES
BODY
CARCINOMAS
DISEASES
FSH
GLANDS
GONADOTROPINS
HORMONES
HYDROXY COMPOUNDS
KETONES
LH
MALE GENITALS
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
ORGANIC COMPOUNDS
ORGANS
PATIENTS
PEPTIDE HORMONES
PITUITARY HORMONES
PROSTATE
RADIOLOGY
RADIOTHERAPY
SECRETION
STEROID HORMONES
STEROIDS
TESTOSTERONE
THERAPY