Fluid shifts in the cat lung during cardiogenic shoc
Journal Article
·
· Adv. Shock Res.; (United States)
OSTI ID:5584432
Transcapillary fluid shifts after experimental myocardial infarction were measured in cats by double-isotope technique. In the control animals, pulmonary extravascular volume increased 49.2% after infarction, and intravascular volume decreased 15.8%. There was evidence of hemoconcentration, with an increase in hematocrit and a fall in plasma volume. Administration of the proteolytic enzyme inhibitor aprotinin following infarction reduced the fluid shift into the extravascular space significantly. It is concluded that the increase in pulmonary extravascular volume frequently seen after myocardial infarction is not solely the result of low output failure but may in part reflect changes in capillary permeability secondary to enzymatic damage.
- OSTI ID:
- 5584432
- Journal Information:
- Adv. Shock Res.; (United States), Journal Name: Adv. Shock Res.; (United States) Vol. 3; ISSN ADSRD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550900* -- Pathology
551000 -- Physiological Systems
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BIOCHEMISTRY
BIOLOGICAL MATERIALS
BLOOD VESSELS
BODY
BODY FLUIDS
CAPILLARIES
CARBOXYLIC ACIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CATS
CHEMISTRY
DISEASES
ENZYME ACTIVITY
HEME
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
LUNGS
MAMMALS
MATERIALS
MYOCARDIAL INFARCTION
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PATHOLOGY
PERMEABILITY
PIGMENTS
PORPHYRINS
RESPIRATORY SYSTEM
VERTEBRATES
VOLUME
551000 -- Physiological Systems
59 BASIC BIOLOGICAL SCIENCES
ANIMALS
BIOCHEMISTRY
BIOLOGICAL MATERIALS
BLOOD VESSELS
BODY
BODY FLUIDS
CAPILLARIES
CARBOXYLIC ACIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
CATS
CHEMISTRY
DISEASES
ENZYME ACTIVITY
HEME
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
LUNGS
MAMMALS
MATERIALS
MYOCARDIAL INFARCTION
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
ORGANS
PATHOLOGY
PERMEABILITY
PIGMENTS
PORPHYRINS
RESPIRATORY SYSTEM
VERTEBRATES
VOLUME