Field emission chemical sensor for receptor/binder, such as antigen/antibody

Patent · Tue Jun 03 00:00:00 EDT 1986

OSTI ID:5580736

Panitz, J A

A field emission chemical sensor is described for specific detection in a liquid sample of molecular amounts of one component of a unique receptor/binder pair, wherein the receptor is a chemical binding partner only for the binder partner. The sensor consists of: an active field emission electrode set comprising: field-electron emission electrode means for field-emission of electrons; and collector electrode means for capturing electrons emitted from the emission electrode; a surface of the emission electrode means having bound thereto only one component of the receptor/binder pair; and sample holding means for holding the liquid sample in simultaneous contact with both electrode means; wherein the magnitude of the electrical current conducted in the sample is indicative of the presence of the other component of the receptor/binder pair contained in the liquid sample.

• Assignee: Dept. of Energy, Washington, DC
• Patent Number(s): US 4592894
• OSTI ID: 5580736
• Country of Publication: United States
• Language: English

Related Subjects

440100* -- Radiation Instrumentation
440300 -- Miscellaneous Instruments-- (-1989)
46 INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY
47 OTHER INSTRUMENTATION
ANTIBODIES
ANTIGENS
CAPTURE
CHEMICAL BONDS
CURRENTS
ELECTRIC CURRENTS
ELECTRODES
ELECTRON CAPTURE
EMISSION
FIELD EMISSION
FLUIDS
LIQUIDS
MEASURING INSTRUMENTS
MEMBRANE PROTEINS
ORGANIC COMPOUNDS
PROTEINS
RECEPTORS
SAMPLE HOLDERS