Effect of cigarette smoke from the mother on bronchial responsiveness and severity of symptoms in children with asthma

Journal Article · Tue Apr 01 04:00:00 EST 1986 · J. Allergy Clin. Immunol.; (United States)

DOI:https://doi.org/10.1016/0091-6749(86)90348-9· OSTI ID:5574871

Murray, A B; Morrison, B J

The effect of parental smoking was assessed in 94 consecutively observed children, aged 7 to 17 years, who had a history of asthmatic wheezing. The 24 children whose mothers smoked, when they were compared with children whose mothers did not smoke, had 47% more symptoms, a 13% lower mean FEV1 percent, a 23% lower mean FEF25-75%, and fourfold greater responsiveness to aerosolized histamine. A dose response was evident. There was a highly significant correlation between the results of the tests and the number of cigarettes the mother smoked while she was in the house. The differences between the children of smoking and nonsmoking mothers were greater in older than in younger subjects. The smoking habits of the father were not correlated with the severity of the child's asthma.

• Research Organization: Univ. of British Columbia, Vancouver
• OSTI ID: 5574871
• Journal Information: J. Allergy Clin. Immunol.; (United States), Journal Name: J. Allergy Clin. Immunol.; (United States) Vol. 4; ISSN JACIB
• Country of Publication: United States
• Language: English

Related Subjects

550900 -- Pathology
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
AGE GROUPS
ASTHMA
CHILDREN
COLLOIDS
DISEASES
DISPERSIONS
DOSE-RESPONSE RELATIONSHIPS
RESIDUES
RESPIRATORY SYSTEM DISEASES
SMOKES
SOLS
TOBACCO SMOKES
TOXICITY