Effect of a short period of fluoride ingestion on dental fluorosis in cattle

Journal Article · Mon Feb 01 04:00:00 EST 1971 · Am. J. Vet. Res.; (United States)

OSTI ID:5564036

Suttie, J W; Faltin, E C

The effects of the ingestion of 2.5 mg of fluoride per kilogram of body weight by dairy heifers during their 13th to 15th or 16th to 18th months of age were studied. This short-term exposure was sufficient to cause severe dental fluorosis in at least one pair of incisors, especially in the 2nd group of heifers, even though the total fluoride intake was not excessive. The plasma fluoride concentrations rapidly increased to 0.5 ppm in both groups of heifers and decreased rapidly after fluoride was removed from the ration. Evidence of dental fluorosis was seen when crown formation was completed before exposure to fluoride and also when the fluoride exposure preceded any calcification of the crown. The most severe effects were seen when the exposure coincided with the initiation of crown formation for a particular incisor. Fluoride analysis of consecutive chronologic sections of the avascular enamel indicated that there was a regular pattern of enamel apposition from the top to the bottom of the crown of one incisor before the top of the crown of the next incisor calcified. 13 references, 3 figures, 3 tables.

• Research Organization: Univ. of Wisconsin, Madison
• OSTI ID: 5564036
• Journal Information: Am. J. Vet. Res.; (United States), Journal Name: Am. J. Vet. Res.; (United States) Vol. 32:2; ISSN AJVRA
• Country of Publication: United States
• Language: English

Related Subjects

560305* -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ACUTE EXPOSURE
ANIMALS
CATTLE
DIGESTIVE SYSTEM
DISTRIBUTION
DOMESTIC ANIMALS
FLUORIDES
FLUORINE COMPOUNDS
HALIDES
HALOGEN COMPOUNDS
INGESTION
INJURIES
INTAKE
MAMMALS
ORAL CAVITY
RUMINANTS
TEETH
TISSUE DISTRIBUTION
TOXICITY
VERTEBRATES