Computer-administered neurobehavioral evaluation system for occupational and environmental epidemiology. Rationale, methodology, and pilot study results
Journal Article
·
· JOM, J. Occup. Med.; (United States)
OSTI ID:5563944
To facilitate the conduct of epidemiologic studies of populations at risk for or suffering from central nervous system (CNS) dysfunction due to environmental agents, a computer-administered neurobehavioral evaluation system has been developed. The system includes a set of testing programs designed to run on a microcomputer and questionnaires to facilitate interpretation of results. Standard tasks evaluating memory, psychomotor function, verbal ability, visuospatial ability, and mood were selected and adapted for computer presentation following the recommendation of an expert committee of the World Health Organization and the National Institute for Occupational Safety and Health. In two pilot surveys, test performance was found to be influenced by age, education level, and socioeconomic status in ways consistent with prior research findings. Performance on tests of short-term memory and reaction time was negatively correlated with intensity of organic solvent exposure among industrial painters. In view of the ease of administration and data handling, high subject acceptability, and sensitivity to the effects of known neurotoxic agents, computer-based assessment of CNS function holds promise for future epidemiologic research.
- Research Organization:
- Harvard School of Public Health, Boston, MA
- OSTI ID:
- 5563944
- Journal Information:
- JOM, J. Occup. Med.; (United States), Journal Name: JOM, J. Occup. Med.; (United States) Vol. 27:3; ISSN JJOMD
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CENTRAL NERVOUS SYSTEM
COMPUTERS
EPIDEMIOLOGY
HAZARDS
HEALTH HAZARDS
INDUSTRIAL PLANTS
INTERNATIONAL ORGANIZATIONS
MEASURING METHODS
MEDICAL SURVEILLANCE
NATIONAL ORGANIZATIONS
NERVOUS SYSTEM
NIOSH
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
PERSONNEL
POLLUTANTS
RESEARCH PROGRAMS
SURVEILLANCE
TESTING
US ORGANIZATIONS
WHO
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CENTRAL NERVOUS SYSTEM
COMPUTERS
EPIDEMIOLOGY
HAZARDS
HEALTH HAZARDS
INDUSTRIAL PLANTS
INTERNATIONAL ORGANIZATIONS
MEASURING METHODS
MEDICAL SURVEILLANCE
NATIONAL ORGANIZATIONS
NERVOUS SYSTEM
NIOSH
OCCUPATIONAL DISEASES
OCCUPATIONAL EXPOSURE
PERSONNEL
POLLUTANTS
RESEARCH PROGRAMS
SURVEILLANCE
TESTING
US ORGANIZATIONS
WHO