Quantitative analysis of the tomographic thallium-201 myocardial bullseye display: critical role of correcting for patient motion

Journal Article · Fri Jan 01 04:00:00 EST 1988 · J. Nucl. Med.; (United States)

OSTI ID:5560324

Eisner, R; Churchwell, A; Noever, T; Nowak, D; Cloninger, K; Dunn, D; Carlson, W; Oates, J; Jones, J; Morris, D

Single photon emission computed tomography (SPECT) myocardial /sup 201/TI imaging appears to offer major improvements over planar imaging. Quantitative analysis of the /sup 201/TI images appears to offer major advantages over subjective analysis in planar imaging, but the three-dimensional data available in SPECT images requires special approaches to analysis and display. Thus, the myocardial bullseye display was developed to summarize and analyze the three-dimensional images of the left ventricle in two dimensions. The relative /sup 201/TI distribution to each region of the left ventricle of an individual patient can be displayed as the number of s.d.s away from normal that the region falls. We found that patient motion during the 22 min required for SPECT imaging appeared to produce artifactual defects. Thus, computer programs were developed to quantitate motion between consecutive frames of a (/sup 201/TI) SPECT myocardial imaging study, simulate nonreturning vertical motion in normal patients, and correct the acquired data for motion. Motion as small as 0.5-1.0 pixel (3-6 mm) in the vertical (axial) direction caused artifactual defects in the quantitative bullseye display that resulted in a false-positive rate of up to 40% for a +1.0 pixel shift. Patient motion of magnitude greater than the threshold value for artifact-production (0.5 pixel) occurred at a rate of 10%, and should be corrected before tomographic reconstruction.

• Research Organization: Emory Univ. School of Medicine, Atlanta, GA
• OSTI ID: 5560324
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 29:1; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
CARDIOVASCULAR SYSTEM
CHEMICAL ANALYSIS
COMPUTER CODES
COMPUTERIZED TOMOGRAPHY
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
ERRORS
HEART
HEAVY NUCLEI
IMAGE PROCESSING
IMAGES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MOTION
MUSCLES
MYOCARDIUM
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PROCESSING
QUANTITATIVE CHEMICAL ANALYSIS
RADIOISOTOPES
SECONDS LIVING RADIOISOTOPES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
THALLIUM 201
THALLIUM ISOTOPES
TOMOGRAPHY