Electrochemical properties of tyrosine phenoxy and tryptophan indolyl radicals in peptides and amino acid analogues
- Ohio State Univ., Columbus (United States)
- Nuclear Research Centre-Negev, Beer Sheva (Israel)
Reported here are the redox potentials of the tyrosine phenoxy (tyrO{sup {sm bullet}}) and tryptophan indolyl (trp{sup {sm bullet}}) radicals in peptides containing tyrosine or tryptophan residues. These were determined with pulse radiolysis, and the electrochemical techniques of cyclic voltammetry and differential pulse polarography. The pulse radiolytic and electrochemical methods yield comparable results. There are small differences (relative to the free amino acid) in redox potentials among the different tryptophan and tyrosine containing peptides; in the case of tryptophan these changes may correlate with the position of amino acid in the peptide. The authors also present the redox potentials of some tyrosine and tryptophan derivatives and the acid/base properties of the tryptophan radical cation, when both free and peptide bound.
- OSTI ID:
- 5542837
- Journal Information:
- Journal of Physical Chemistry; (United States), Journal Name: Journal of Physical Chemistry; (United States) Vol. 95:8; ISSN 0022-3654; ISSN JPCHA
- Country of Publication:
- United States
- Language:
- English
Similar Records
Oxidation of tryptophan and N-methylindole by N sub 3 sup sm bullet , Br sub 2 sup sm bullet minus , and (SCN) sub 2 sup sm bullet minus radicals in light- and heavy-water solutions: A pulse radiolysis study. [Accelerated electrons]
Effect of oxygen on the radiolysis of tyrosine in aqueous solutions
Related Subjects
140505 -- Solar Energy Conversion-- Photochemical
Photobiological
& Thermochemical Conversion-- (1980-)
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400500* -- Photochemistry
ABSORPTION SPECTROSCOPY
AMINO ACIDS
AQUEOUS SOLUTIONS
AROMATICS
AZAARENES
AZOLES
BEAMS
CARBOXYLIC ACIDS
CHEMICAL RADIATION EFFECTS
CHEMICAL REACTION KINETICS
CHEMICAL REACTIONS
CHEMISTRY
DATA
DECOMPOSITION
DERIVATIZATION
DISPERSIONS
ELECTROCHEMISTRY
ELECTRON BEAMS
ENERGY RANGE
EXPERIMENTAL DATA
HETEROCYCLIC ACIDS
HETEROCYCLIC COMPOUNDS
HYDROXY ACIDS
INDOLES
INFORMATION
KINETICS
LEAST SQUARE FIT
LEPTON BEAMS
MATHEMATICAL MODELS
MAXIMUM-LIKELIHOOD FIT
MEV RANGE
MIXTURES
NUMERICAL DATA
NUMERICAL SOLUTION
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PARTICLE BEAMS
PEPTIDES
PH VALUE
PHENOXY RADICALS
POLAROGRAPHY
PROTEINS
PYRROLES
RADIATION EFFECTS
RADICALS
RADIOLYSIS
REACTION KINETICS
REDOX POTENTIAL
SOLUTIONS
SPECTROSCOPY
THERMODYNAMICS
TITRATION
TRYPTOPHAN
TYROSINE
VOLTAMETRY