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Mechanism of intramolecular cycloalkylation of 3-methyl-3-phenyl-1-butanol in the presence of D sub 3 PO sub 4

Journal Article · · Journal of Organic Chemistry of the USSR (English Translation); (USA)
OSTI ID:5523855
The intramolecular cycloalkylation of isomeric 2-methyl-4-phenyl-2-butanol and 3-methyl-3-phenyl-1-butanol in D{sub 3}PO{sub 4} is accompanied by hydrogen exchange with the formation of deuterated 1,1-dimethylindane. The distribution of the deuterium in the polymethylene ring shows that the reaction of the first alcohol takes place as a result of C{sub 5}-cyclization of the {gamma}-phenylalkyl cation, whereas the reaction of the second alcohol takes place by direct C{sub 5}-cyclization and by cyclization of the {gamma}-phenylalkyl cations formed as a result of 1,2- and 1,3-transfers of the phenyl group.
OSTI ID:
5523855
Journal Information:
Journal of Organic Chemistry of the USSR (English Translation); (USA), Journal Name: Journal of Organic Chemistry of the USSR (English Translation); (USA) Vol. 24:8; ISSN 0022-3271; ISSN JOCYA
Country of Publication:
United States
Language:
English