/sup 125/I Vicryl suture implants as a surgical adjuvant in cancer of the head and neck

Journal Article · Fri Feb 01 04:00:00 EST 1985 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(85)90164-6· OSTI ID:5519771

Goffinet, D R; Martinez, A; Fee, Jr, W E

Sixty-four intraoperative /sup 125/I seed implants using absorbable suture (Vicryl) carriers were performed in 53 patients with head and neck cancers at Stanford between 1975 and 1980. In previously untreated patients, local control in the implanted volume or in all head and neck sites was obtained in 79 and 71%, respectively. Of 34 patients with recurrent carcinomas, local control was obtained in the implant volume in 20 (59%), while 38% had no recurrence post-implantation in any head and neck site. The incidence of complications is correlated with /sup 125/I radiation doses, total millicuries inserted, seed strength used, and tissue volume implanted for both untreated patients and those with local recurrences. Guidelines for the optimal use of the above 4 parameters are also presented. The authors conclude that /sup 125/I seed Vicryl intraoperative suture implants are an effective surgical adjuvant in the treatment of advanced, previously untreated or recurrent head and neck cancers.

• Research Organization: Stanford Univ. Medical Center, CA
• OSTI ID: 5519771
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 11:2; ISSN IOBPD
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
HEAD
IMPLANTS
INJURIES
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
JAW
LOCAL RADIATION EFFECTS
MATERIALS
MEDICAL SUPPLIES
MEDICINE
NECK
NECROSIS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
OSTEORADIONECROSIS
PATHOLOGICAL CHANGES
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIATION INJURIES
RADIATION SOURCE IMPLANTS
RADIATION SOURCES
RADIOINDUCTION
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SIDE EFFECTS
SKELETAL DISEASES
SKELETON
SKULL
SURGERY
SURGICAL MATERIALS
THERAPY