Complementary roles of CT and /sup 131/I-MIBG scintigraphy in diagnosing pheochromocytoma

Journal Article · Sat Oct 01 04:00:00 EDT 1983 · AJR, Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.141.4.719· OSTI ID:5504630

Francis, I R; Glazer, G M; Shapiro, B; Sisson, J C; Gross, B H

Recently /sup 131/I-MIBG (metaiodobenzylguanidine), an adrenergic tissue-localizing radiopharmaceutical, has been used for diagnosis of pheochromocytoma. In a retrospective study of 32 patients with pathologically proved primary, metastatic, or recurrent pheochromocytoma, the roles of /sup 131/I-MIBG scintigraphy and computed tomography (CT) in pheochromocytoma detection were compared. The two methods were equally accurate in the identification of primary and recurrent pheochromocytoma. /sup 131/I-MIBG scanning was more accurate as the initial examination in patients with extraadrenal tumors. In patients with metastatic disease, scintigraphy was preferable to CT because of its nontomographic nature, which permitted imaging of the entire body. Although a positive MIBG scan is diagnostic of pheochromocytoma, CT of extraadrenal tumors (particularly in the chest) has been very useful in planning appropriate surgical intervention. Furthermore, the roles of /sup 131/I-MIBG scintigraphy and CT in the detection of pheochromocytoma are complementary because each method has certain limitations.

• Research Organization: Department of Radiology, University of Michigan Medical Center, Ann Arbor
• OSTI ID: 5504630
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 141:4; ISSN AAJRD
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
ADRENAL GLANDS
AROMATICS
AUTONOMIC NERVOUS SYSTEM
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BODY
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
HALOGENATED AROMATIC HYDROCARBONS
INTERMEDIATE MASS NUCLEI
IODINATED AROMATIC HYDROCARBONS
IODINE 131
IODINE ISOTOPES
ISOTOPES
METASTASES
NEOPLASMS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANIC IODINE COMPOUNDS
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
TOMOGRAPHY