Prevention of deep vein thrombosis and pulmonary embolism. [/sup 125/I]

Journal Article · Wed Mar 01 00:00:00 EST 1978 · Am. J. Surg.; (United States)

DOI:https://doi.org/10.1016/0002-9610(78)90078-8· OSTI ID:5504521

Le Quesne, L P

The development of the /sup 125/I-fibrinogen technic in the diagnosis of postoperative deep vein thrombosis provides a valuable tool for the study of the condition itself and of the efficacy of prophylactic measures. These measures may be divided into two groups: the antistasis regimes and the antithrombotic regimes. Published reports based on the /sup 125/I-fibrinogen technic are critically reviewed. Although many regimes cause a significant diminution in the incidence of isotopically detected deep vein thrombosis, 90% of which are confined to the calf, this does not necessarily imply a similar diminution in the incidence of major pulmonary emboli, most of which arise from thrombi in the proximal segment of the lower limb veins. The origin of these proximal thrombi, with particular reference to their relationship to calf thrombi, is discussed. The reported studies of the influence of antithrombotic regimes on the incidence of pulmonary embolism are reviewed. It is concluded that a reduction in the incidence of isotopically detected deep vein thrombosis is probably accompanied by a significant reduction in the incidence of major pulmonary embolism, but further studies are required.

• OSTI ID: 5504521
• Journal Information: Am. J. Surg.; (United States), Vol. 135:3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
BLOOD VESSELS
SCINTISCANNING
FIBRINOGEN
TRACER TECHNIQUES
IODINE 125
LUNGS
THROMBOSIS
DIAGNOSIS
EMBOLI
BETA DECAY RADIOISOTOPES
BLOOD COAGULATION FACTORS
BODY
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GLOBULINS
INTERMEDIATE MASS NUCLEI
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques