Evaluation of human thyroid tumors by proton nuclear magnetic resonance
Proton nuclear magnetic resonance (NMR) was used in a study of 40 patients with thyroid tumors following partial or total thyroidectomy. Three patient groups were considered: those with nodules showing increased uptake, those with solitary nodules with decreased uptake, and those with multinodular goiters. Spin-lattice and spin-spin relaxation times (T/sub 1/ and T/sub 2/) were measured on samples of nodular and extranodular tissue from each patient. Increased T/sub 1/ and T/sub 2/ were observed for benign cold nodules, an increase in T/sub 1/ alone for nodules with increased uptake, and a wide fluctuation in T/sub 1/ and T/sub 2/ for multinodular goiters. The four cancers in the series did not show a distinctive proton NMR pattern in comparison with the other nodular structures studied. The results point to the feasibility of applying NMR techniques to the detection of thyroid disease.
- Research Organization:
- Centre Eugene Marquis, Rennes, France
- OSTI ID:
- 5504061
- Journal Information:
- J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 23:1; ISSN JNMEA
- Country of Publication:
- United States
- Language:
- English
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550602* -- Medicine-- External Radiation in Diagnostics-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BODY
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ENDOCRINE GLANDS
GLANDS
MAGNETIC RESONANCE
NEOPLASMS
NUCLEAR MAGNETIC RESONANCE
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RESONANCE
SCINTISCANNING
THYROID
UPTAKE