Indium-111-labeled platelets in monitoring human pancreatic transplants

Journal Article · Fri Sep 01 00:00:00 EDT 1989 · Journal of Nuclear Medicine; (USA)

OSTI ID:5481019

Catafau, A M; Lomena, F J; Ricart, M J; Pons, F; Piera, C; Pavia, J; Moragas, M; Garcia, A; Herranz, R; Andreu, J ^[1]

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1. Nuclear Medicine Service, Barcelona (Spain)

We have performed 59 {sup 111}In-labeled platelet scintigraphies in 12 patients with pancreas transplant, and we have compared retrospectively the {sup 111}In platelet uptake with the graft immunological situation. A diffuse uptake in the graft was seen in five of six patients with pancreatic rejection. The scans became positive before changes in biochemical tests were detected. No {sup 111}In platelet uptake was seen in five of seven normally functioning grafts. Two cases of venous thrombosis and two perigraft hematomas appeared like a focal {sup 111}In platelet accumulation. Indium-111-labeled platelet scintigraphy can be a useful method for monitoring pancreas transplants. It may be helpful in the early detection of pancreatic allograft rejection and in the differential diagnosis between this and other complications such as thrombosis or hematomas.

• OSTI ID: 5481019
• Journal Information: Journal of Nuclear Medicine; (USA), Journal Name: Journal of Nuclear Medicine; (USA) Vol. 30:9; ISSN 0161-5505; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BLOOD PLATELETS
BODY
BODY FLUIDS
CARDIOVASCULAR DISEASES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIABETES MELLITUS
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIGESTIVE SYSTEM
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
ENDOCRINE DISEASES
ENDOCRINE GLANDS
GLANDS
GRAFT-HOST REACTION
INDIUM 111
INDIUM ISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
KIDNEYS
MATERIALS
METABOLIC DISEASES
MINUTES LIVING RADIOISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PANCREAS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SCINTISCANNING
THROMBOSIS
TRANSPLANTS
VASCULAR DISEASES